Comparison of the Effect of 24-Hour Drip and Routine IV Acetaminophen on Pain Control in Patients Undergoing Cesarean Section

Background: Pain relief after C/S is very important. Acetaminophen is one of the most common drugs to control post-operative pain. Due to the fact that Acetaminophen IV should be injected several times a day for patients, to save time, manpower and cost, it is recommended to inject intravenous Acetaminophen in 24-hour drip. Therefore, this study was designed and performed to compare Acetaminophen drip with routine IV injection on pain control after C/S surgery. Methods: This interventional study was performed on 80 women who referred to Isfahan Family Hospital for C/S in 1396. Patients were divided into two groups of 24-hour drip and routine IV injection of Acetaminophen. Then postoperative pain and complications were evaluated in recovery and within 24 hours after surgery. Finally, the data were analyzed using SPSS. Results: The mean score of postoperative pain in both groups was statistically significant (P-Value <0.05). The mean pain score in the Acetaminophen drip group was significantly lower than the routine IV Acetaminophen group (P-Value = 0.014). Mean Diastolic Blood Pressure in routine IV Acetaminophen group was significantly higher than Acetaminophen drip group (P-Value = 0.004). Drug side effects were higher in the routine IV Acetaminophen group.  Conclusion:  This study showed that 24-hour Acetaminophen drip had better analgesic effects with fewer side effects than routine IV Acetaminophen injection after C/S surgery.